Clinical Trials Experience
Number of active clinical trials | 16 |
Number of participants screened in 2020 | 163 |
Number of participants enrolled in trials in 2020 | 128 |
Dermatological conditions | Atopic dermatitis, plaque psoriasis, scalp psoriasis, hand eczema, alopecia areata, vitiligo and hidradenitis suppurativa |
Participant population | Adolescents and adults |
A selected listing of trials undertaken at The Skin Hospital:
Sponsor, Protocol ID, Long title
Abbvie, M16046, A Phase 3b Multicenter, Randomized, Double-Blind, Double-Dummy, Active Controlled Study Comparing the Safety and Efficacy of Upadacitinib to Dupilumab in Adult Subjects with Moderate to Severe Atopic Dermatitis
Abbvie, M19850, A Phase 3b, open-label treatment extension study of upadacitinib for the treatment of adult subjects with moderate to severe atopic dermatitis who completed treatment in Study M16-046
Abbvie, M18891, A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Adolescent and Adult Subjects with Moderate to Severe Atopic Dermatitis
Arcutis, ARQ-154-204, A Phase 2b, 8-Week, Parallel Group, Double Blind, Vehicle-Controlled Study of the Safety and Efficacy of ARQ-154 Foam 0.3% Administered QD in Adolescents and Adults with Scalp and Body Psoriasis
Arcutis, ARQ-252-205, A Phase 1 and 2, Multiple Dose and 12-Week, Parallel Group, Double Blind, Dose Ranging, Vehicle-Controlled Study of the Safety and Efficacy of ARQ-252 Cream 0.1% and ARQ-252 Cream 0.3% in Subjects with Chronic Hand Eczema
Botanix, BTX.2018.003, A Randomized, Double-Blind, Vehicle-Controlled Study of the Safety, Tolerability and Efficacy of BTX 1204 in Patients with Moderate Atopic Dermatitis
Dermira, DRM06-AD04/J2T-DM-KGAB, A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Lebrikizumab in Patients with Moderate-to-Severe Atopic Dermatitis
Dermira, DRM06-AD17, An Open-Label, Single-Arm Study to Assess the Safety and Efficacy of Lebrikizumab in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis
Lilly, I4V-MC-JAHN(c), A Phase 3 Multicenter, Double-Blind Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Adult Patients with Atopic Dermatitis
Lilly, I4V-MC-JAHN(7.1), Protocol Addendum I4V-MC-JAHN(7.1) A Phase 3 Multicenter, Double-Blind Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Adult
Patients with Atopic Dermatitis
Lilly, I4V-MC-JAIR(c), A Multicenter, Randomized, Double-Blind, Placebo- Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Baricitinib in Adult Patients with Severe or Very Severe Alopecia Areata
Galderma, RD.06.SPR.118161, A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Subjects with Moderate-to-Severe Atopic Dermatitis
Galderma, RD.06.SPR.118163, A Prospective, Multicenter, Long-Term Study to Assess the Safety and Efficacy of Nemolizumab (CD14152) in Subjects with Moderate-to-Severe Atopic Dermatitis
Janssen, CNTO1959PSO3001, A Phase 3, Multicenter, Randomized, Double-blind, Placebo and Active Comparator-controlled Study Evaluating the Efficacy and Safety of Guselkumab for the Treatment of Subjects with Moderate to Severe Plaque-type Psoriasis
LeoPharma, LP0133-1275, A phase 2b, double-blind, randomised, 5-arm, vehicle-controlled, dose-ranging trial to evaluate the efficacy and safety of twice daily topical applications of delgocitinib cream 1, 3, 8, 20 mg/g for 8 weeks in adult subjects with mild to severe atopic dermatitis
LeoPharma, LP0162-1326, A Randomised, Double-blind, Placebo-Controlled, phase 3 trial to Evaluate the Efficancy and Safety of Tralokinumab Monotherapy in Subjects eith Moderate-to-Severe Atopic Dermatitis who are Candidates for Systemic Therapy
LeoPharma, LP0162-1334, A randomised, double-blind, placebo-controlled, parallel-group, multi-centre trial to evaluate the efficacy, safety, and tolerability of tralokinumab monotherapy in adolescent subjects with moderate-to-severe atopic dermatitis who are candidates for systemic therapy
Novartis, QGE031C2303, A multi-center, randomized, double-blind, active and placebo-controlled study to investigate the efficacy and safety of ligelizumab (QGE031) in the treatment of Chronic Spontaneous Urticaria (CSU) in adolescents and adults inadequately controlled with H1-antihistamines
Pfizer, B7451036, A phase 3, randomised, double-blind, placebo-controlled, multi-centre study investigating the efficacy and safety of PF-04965842 co-administered with background medicated topical therapy in adolescent participants 12 to <18 years of age with moderate-to-severe atopic dermatitis
Pfizer, B7451015, A phase 3 multi-center,long-term extensions study investigating the efficacy and safety of abrocitinib, with or without topical medications, administered to subjects aged 12 years and older with moderate to severe atopic dermatitis
Pfizer, B7981019, phase 2b randomised, double-blind, placebo-controlled, multicenter, dose-ranging study to evaluiate the efficacy and safety profile of PF-06651600 with a partially blinded extension period to evaluate the efficacy and safety of PF-06651600 AND PF-06700841 in subjects with active non-segmental vitiligo
Pfizer, C2501007, phase 2A multicenter, randomized, double-blind, placebo-controlled, 16-week study evalutating the safety and efficacy of PF-06650833, PF-06700841, and PF-06826647 in adults with moderate to severe hidradenitits suppurativa