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Understanding and Management of Patients with a High Burden of Keratinocyte Cancer

Prof Khosrotehrani

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Speaker:Professor Kiarash Khosrotehrani
Where:Founders Wing, The Skin Hospital, 121 Crown St, Darlinghurst
Who should attend:Dermatologists and Dermatology Registrars
Overview:This presentation will explore skin cancer development, specifically focusing on how sun-exposure results in mutations in our skin cells that progress towards skin cancer. Professor Khosrotehrani will discuss how this understanding of mutations is essential in preventing cancer formation in our current practice. He will explore the issue and burden of keratinocyte cancers, especially in relation to organ transplantation in QLD.

He will explain the use of a series of experimental models to address this problem, illustrating the progress his team and others have made in the field of skin cancer formation at the genetic and genomic level. A number of early clinical trials run by his group based on these laboratory findings will also be revealed.

About the speaker:Professor Khosrotehrani is a clinical scientist, dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads a research group at the University of Queensland Diamantina Institute within the newly established Translational Research Institute in Brisbane, Australia. He is also the deputy director of the Australian Skin and Skin Cancer Research Centre in Brisbane. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialised in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.

During his post-doctoral training at Tufts-New England Medical Centre, Boston, USA, Dr. Khosrotehrani helped establish the contribution of feotal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). He is currently a fellow of the NHMRC of Australia. The main focus of his laboratory, the Experimental Dermatology Group, is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how this stem cell response contributes to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.

RSVP:21st October 2019, 17:00 PM


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